Until now there was no method to diagnose/monitor human brain edema in the FIRST CRITICAL HOUR of a head injury. To diagnose/monitor whether the brain is swelling a surgery must be performed – ICP (Intracranial pressure monitoring) required at Glasgow Coma Scale ≤ 8


The worldwide first medical device designed to study changes in the subarachnoid space and intracranial pulse parameters

Method: NIR-T/BSS

Near InfraRed Transillumination with Back-Scattering Sounding to non-invasively measure changes in pial artery pulsation (cc-TQ) and subarachnoid width (sas-TQ).

Monitoring Device


The SAS Monitor allows non-invasive continuous monitoring of the Subarachniod Space and is designed for long-term monitoring of adults.


No surgery,
No surgery scars,
Continous monitoring,
Quick medical response


FIG. 1

Correlation diagram of changes in width of subarachnoid space in humans when switching from a lying-back position to an abdominal-lying position using NIR-T/BSS and MRI. Frydrychowski et al. Subarachnoid space: new tricks by an old dog. PLoS One. 2012;7:e37529.


FIG. 2

Effect of acute compression of subarachnoid space in humans on NIR-T/BSS variables: cc-TQ is ‘‘cut’’ by the narrowing subarachnoid space. Sharp edges of the cc-TQ waves are visible at the distant sensor (DS) and cc-TQ (enhanced tracings). cc-TQ – cardiac component of transillumination quotient (pial artery pulsation); mW/cm2 – microwatt/centimetre2. Frydrychowski et al. Influence of acute jugular vein compression on the cerebral blood flow velocity, pial artery pulsation and width of subarachnoid space in humans. PLoS One. 2012;7:e48245.


FIG. 3

Effects of single boluses of saline into the subdural space of the spinal cord in the lumbar region in rabbits on the recorded variables: (A) sas-TQ (NIR-T/BSS): an elevation of the tracing indicates an increase in the width of the SAS, (B) cc-TQ (NIR-T/BSS): an increase in the amplitude of cc-TQ indicates an increase in the amplitude of pulsation of the pial artery, (C) intracranial pressure (mm Hg), (D) pressure in intracranial portion of the internal carotid artery (mm Hg). Boluses are indicated with vertical arrows. Frydrychowski et al. Use of Near Infrared Transillumination / Back Scattering Sounding (NIR-T/BSS) to assess effects of elevated intracranial pressure on width of subarachnoid space and cerebrovascular pulsation in animals. Acta Neurobiol Exp. 2011;71:313-21.